Strontium

Strontium is a naturally occurring trace element chemically similar to calcium. It is found in small amounts in bone mineral, where it substitutes for calcium in hydroxyapatite. Strontium ranelate was...

• Strontium Ranelate (Prescription Drug) Demonstrated Significant Reductions In Vertebral And Hip Fracture Risk In Postmenopausal Women With Osteoporosis In Phase Iii Trials
• Incorporated Into Bone Mineral In Place Of Calcium, Increasing Bone Mineral Density Measurements (Note: Some Increase Reflects Strontium's Higher Atomic Mass)
• Strontium Ranelate Had Dual Activity: Stimulating Osteoblast (Bone-Forming) Activity And Inhibiting Osteoclast (Bone-Resorbing) Activity
• Low-Dose Dietary Strontium From Food And Water Is Generally Well-Tolerated And May Contribute Modestly To Bone Mineral Content

Note No established dietary RDA or UL; strontium ranelate was a prescription medication, not a supplement Note Strontium ranelate was withdrawn or severely restricted in most markets (including Europe) due to increased risk of serious cardiovascular events (MI, stroke) and rare but severe skin reactions (DRESS syndrome)