Hormones & Metabolism
Arsenic
As — Element #33
Arsenic is a metalloid classified as an ultratrace element with highly controversial and unconfirmed conditional essentiality. Animal studies suggest inorganic arsenic deprivation at extremely low lev...
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- Animal Deficiency Studies (Rats, Hamsters, Goats, Chickens) On Ultra-Low Arsenic Diets Show Impaired Growth, Reproductive Failure, And Metabolic Abnormalities — Suggesting Possible Essentiality At Sub-Microgram Levels
- Organic Arsenobetaine Found In Seafood Is Considered Non-Toxic And Non-Essential; It Passes Through The Body Largely Unchanged
- Arsenic Trioxide (Trisenox) Is An Fda-Approved Chemotherapy Agent For Acute Promyelocytic Leukemia — A Specific Pharmacological Application, Not Nutritional
- No Confirmed Essential Function Has Been Identified In Humans At Any Dietary Intake Level
Note No RDA established; no safe supplemental dose defined — arsenic is primarily approached from a toxicology standpoint Note Inorganic arsenic is a Group 1 human carcinogen (IARC); chronic low-level exposure via drinking water is associated with bladder, lung, and skin cancers