SO DYK
THYROID FUNCTION

Boron

B — Element #5

also known as Boric acid, Borax, Calcium fructoborate, Boron citrate

Boron is an ultratrace mineral found in fruits, vegetables, legumes, and nuts. While no RDA has been established, boron appears to influence steroid hormone metabolism, bone mineral density, and brain function. Animal studies demonstrate it is essential for normal bone development and reproduction, and it may modulate the metabolism of vitamin D, estrogen, and testosterone.

  • May augment or mimic estrogen and testosterone effects, potentially supporting bone mineral density in postmenopausal women
  • Animal studies suggest boron is required for normal bone formation and is synergistic with vitamin D in calcium metabolism
  • Associated with improved cognitive performance (attention, memory) in observational studies
  • May reduce inflammatory markers (CRP, TNF-α) at doses of 3–6 mg/day in some trials
  • Plays a role in modulating the use of energy substrates (carbohydrate, fat) in cell membranes

Active in B(OH)₃ (boric acid), B(OH)₄⁻ (borate).

Tolerable Upper Intake Level (UL): 20 mg/day for adults
High doses (above UL) can cause nausea, vomiting, diarrhea, skin rash, and in severe cases kidney damage
Boron has estrogenic activity and should be used cautiously by individuals with hormone-sensitive conditions (e.g., breast, uterine, or ovarian cancer)
Evidence supporting boron supplementation for specific health outcomes in humans is preliminary and insufficient to establish an RDA