GENERAL IMMUNITY

Reishi

Ganoderma lucidum

also known as Lingzhi, Mushroom of immortality

Moderate

A glossy red-brown shelf mushroom called 'lingzhi' in Chinese — the herb of immortality. Used in traditional Chinese medicine for over two thousand years as a tonic for vitality and longevity, reishi has more modern research behind it than most medicinal mushrooms. Effects are gentle, work over weeks to months, and lean toward immune balance and stress support.

Modulates immune function — can both support a sluggish response and gentle an overactive one
Adaptogen — helps the body cope with stress
Supports sleep and eases mild anxiety in traditional use
Used as a supportive add-on alongside conventional cancer treatment in parts of Asia — improves quality of life and may reduce some treatment side effects
May modestly support cardiovascular health — small effects on blood pressure and cholesterol
Rich in beta-glucans, the same immune-active polysaccharides found in other medicinal mushrooms
Long traditional reputation as a longevity tonic

Active in Beta-glucans, Triterpenes (ganoderic acids), Polysaccharides.

Mild blood-thinning effect — caution with blood thinners

Stop two weeks before surgery

Skip with autoimmune conditions without provider guidance — reishi affects immune signaling

Use caution with immunosuppressants

Use caution with blood pressure medications — additive lowering

Use caution with diabetes medication — may lower blood sugar

Skip during pregnancy and nursing — limited safety data

Generally well tolerated; mild stomach upset, dizziness, and dry mouth occasionally reported

Memorial Sloan Kettering About Herbs · EMA Herbal Medicinal Product Monographs · American Botanical Council HerbMedPro

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