Ginkgo
Ginkgo biloba
also known as Maidenhair tree, Silver apricot
Moderate
An ancient tree whose leaf extract has been used to support circulation, cognitive function, and peripheral vascular health.
- Supports peripheral circulation
- May support cognitive function in older adults
- May ease intermittent claudication (leg pain on walking)
- May ease tinnitus in some studies
- Provides antioxidant flavonoids
- Inhibits platelet-activating factor
- From a tree species 270 million years old
Active in Ginkgolides, Bilobalide, Flavonoid glycosides, Quercetin.
Significant bleeding risk with blood thinners — major concern
Discontinue 2 weeks before surgery
May trigger seizures — avoid with seizure disorders
May lower blood sugar — caution with diabetes medication
Raw seeds are toxic
Avoid in pregnancy and nursing
Research
- Ginkgolic acid targets HSPA8 to trigger ferroptosis in hepatocellular carcinoma via chaperone-mediated autophagy-dependent GPX4 degradation.
- Effect of a combination of Ginkgo biloba leaf extract and triangle health management in patients with ischemic vertigo- An exploratory investigation.
- Network pharmacology and machine learning reveal multi-target mechanisms of poly herbal formulation against atherosclerosis.
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