Know what you're putting in your body.

158 herbs, nutrients, and compounds. What the science says, what tradition knew, and what to watch for. Founding members keep this running.

$60 /year

Founding rate — locked for life. Regular price after launch: $96/year.

✓ Full access to all 158+ entries
✓ Print-ready reference card for every herb
✓ Monthly curated set — 5 herbs, one body system
✓ The Sunday Letter — weekly research digest
✓ Bookmarks synced across devices
✓ Founding rate locked forever

Become a founding member

Cancel any time. No questions asked.

HEART FUNCTION

Pomegranate

Punica granatum

also known as pomegranate fruit, pomegranate extract

Moderate

Pomegranate — Köhler 1887 botanical illustration

An ancient Middle Eastern fruit named in nearly every old medical tradition — Egyptian, Greek, Ayurvedic, Persian, biblical. Modern research focuses on the seed-arils and juice, which are exceptionally rich in antioxidants. The most consistent evidence is for cardiovascular and prostate support.

Modestly lowers blood pressure with daily juice or extract
Modestly improves blood vessel function — measured as flow-mediated dilation
Powerful antioxidant action from punicalagins, the main polyphenols in the fruit
May slow the rise of PSA in men with prostate cancer who have completed treatment
Anti-inflammatory action documented in multiple settings
Long traditional use as a fertility and longevity fruit
Most evidence comes from the juice, the arils (seed pulps), and standardized extracts — not the rind

Pomegranate juice can interact with certain medications by affecting how the liver processes them — caution with statins, blood pressure medications, and blood thinners

Use caution with diabetes medication — juice contains real sugar even though it improves long-term blood sugar regulation

Skip the rind and root bark in any quantity — both are toxic

Skip large medicinal doses during pregnancy — culinary amounts are fine

Research

Ameliorative potential of pomegranate juice against synthetic colorant (E124)-induced biochemical and histopathological changes in the rat brain and testes.
Alqahtani NS, Hassan HM, Rashied RM · Food chemistry. Molecular sciences · 2026
Therapeutic effects of pomegranate hot-water extract via inhibition of apoptosis and oxidative stress in a DHEA-induced mouse model of PCOS.
Moon S, Oh Y, Noh H · Integrative medicine research · 2026
Phytochemicals as inhibitors of pathogenesis to combat ostertagiosis, toxocariasis, trichostrongylosis and trichuriasis in cattle: A systematic review.
Hayat H, Abbas S, Zaman MA · Microbial pathogenesis · 2026

NCCIH — Pomegranate · MedlinePlus Herbs & Supplements · NIH NCCIH Herbs at a Glance

You might also explore

The curious few.

50 founding spots left