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Wild Yam
also known as colic root
A North American climbing vine whose root has a long traditional use for menstrual cramps, digestive complaints, and joint pain. Wild yam contains diosgenin, a plant compound that pharmaceutical chemists used in the 1940s as a starting point to synthesize progesterone, cortisone, and birth control hormones in the lab. But the body cannot do this same conversion — wild yam itself does not produce hormones in the body, despite extensive marketing claims to the contrary.
- Traditional use for menstrual cramps and painful periods — the antispasmodic effect is the genuine traditional use
- Long traditional use for digestive cramping and irritable bowel-type complaints
- Mild anti-inflammatory action useful for joint and muscle discomfort
- Diosgenin (the plant steroid) was the laboratory starting point for synthetic progesterone, cortisone, and the first birth control pills — a real piece of pharmaceutical history
- Topical wild yam creams have been marketed for menopause and PMS, though the human body cannot convert diosgenin to progesterone — any effect from these creams comes from added synthetic progesterone, not the wild yam itself
- The Combination of Diosgenin, Vitamin D, and α-Lactalbumin Normalizes the Menstrual Cycle in Women with PCOS of Phenotype D: A Pilot Clinical Study.
- Chemosensitization and Molecular Docking Assessment of Dio-NPs on Resistant Breast Cancer Cells to Tamoxifen.
- Herbal Treatment of Female Urogenital Atrophy: A Retrospective Cohort Analysis.
Memorial Sloan Kettering About Herbs · EMA Herbal Medicinal Product Monographs · American Botanical Council HerbMedPro · Memorial Sloan Kettering About Herbs · EMA Herbal Medicinal Product Monographs · American Botanical Council HerbMedPro
Know what you're putting in your body.
158 herbs, nutrients, and compounds. What the science says, what tradition knew, and what to watch for. Founding members keep this running.
Founding rate — locked for life. Regular price after launch: $96/year.
- ✓ Full access to all 158+ entries
- ✓ Print-ready reference card for every herb
- ✓ Monthly curated set — 5 herbs, one body system
- ✓ The Sunday Letter — weekly research digest
- ✓ Bookmarks synced across devices
- ✓ Founding rate locked forever
Cancel any time. No questions asked.